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《Advanced Biomaterials for Biomedical Engineering》


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Biomedical engineering is the key technology of the 21st century. The possibility to exploit the structures and process of advanced materials for novel functional materials, biosensors, stem cells technology, regenerative medicine, drug delivery systems has created the rapidly growing field of biomaterials technology. Designed as a broad survey of the field, this book combines contributions from molecular biology, materials science and medicine to fathom the full scope of current and future developments.

It is divided into four main sections:

?Interface systems
?Physiochemical properties
?Structures of biomaterials
?Medical applications

Each chapter describes in detail currently valuable methods and contains numerous references to the primary literature, making this the perfect “filed guide” for chemists, biologists and physicians who want to explore the fascinating world of biomedical engineering.

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  作者介紹

  
  
  
  
  
  Hossein Hosseinkhani
  
  Professor Hossein Hosseinkhani received his Ph.D degree in Polymer Chemistry in the field of Biomedical Engineering from Kyoto University, Japan (1998-2002). Dr. Hosseinkahni has broad experience in life sciences and is expert in nanotechnology, biomaterials and stem cells technology for regenerative medicine and biomedical engineering applications. He has been awarded several prestigious fellowships including JSPS Fellowship of Japan at Institute for Frontier Medical Sciences, Kyoto University Hospital (2002–2004), ICYS Research Fellow of Japan at Notational Institute for Materials Science (2004–2008), IRIIMS Research Fellow of Japan at International Research Institute for Integrated Medical Sciences, Tokyo Women’s Medical University (2008–2009), and Visiting Scientist at Center for Biomedical Engineering, Massachusetts Institute of Technology (MIT), USA (2007–2009). Dr. Hosseinkhani has 50 issued Japan and U.S. patents, several U.S. patents pending and has authored over 100 international publications in prestigious international journals and over 200 presentations at international conferences till present time. Currently, he is Director of Bioengineering Program and Professor at the Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology (Taiwan Tech).
  
  Keng-Liang Ou
  
  Professor Keng-Liang Ou graduated from Mechanical Engineering Ph.D. program at National Chiao Tung University, Taiwan. Professor Ou came to Taipei Medical University to pursuit on biomaterial research and development and he becomes the current elected Dean of College of Oral Medicine in Taipei Medical University, Taiwan. He is also in charge of Graduate Institute of Biomedical Materials and Tissue Engineering, Research Center for Biomedical Implants and Microsurgery Devices and Research Center for Biomedical Devices and Prototyping Production. Besides the institutional positions, he is the President of Institute of Plasma Engineering Taiwan, the leader of The Taiwan society for metal heat treatment and the Head Taiwan Oral Biomedical Engineering Association. Professor Ou focuses his researches on, Biomaterials, Bioengineering, Nanotechnology, and Biomedical Devices. He is the leader and organizer for the biomedical product design, production, manufacturing, testing, legalization and market planning, with supports from team of scientists and researchers with different expertise. Professor Ou was honorably awarded with the 49th Ten Outstanding Young Persons of Taiwan on 2011.
  
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• Chapter 1 Introduction to Biomaterials
  Chapter 2 Biomedical Materialxs
  2.1 Introduction
  2.2 Biodegradable Polymers
  2.3 Natural Biomaterials
  2.4 Biodegradable Nanoparticles
  2.5 Controlled Release Drug Delivery Systems
  using Biomaterials
  References
  Chapter 3 Physical Properties of Biomaterials
  3.1 Physical properties of materials
  3.2 Introduction of spectroscopy
  3.3 Thermal properties
  3.4 Thermal analysis
  Reference
  Chapter 4 Mechanical Behavior of Biomaterials
  4.1 Introduction
  4.2 Mechanics of Materials
  4.3 Mechanical Testing
  4.4 Fracture of Materials
  References
  Chapter 5 Hydrogels in Medicine
  5.1 Introduction
  5.2 Mechanical properties of hydrogels and
  interpenetrating networks
  5.3 Engineering hydrogels with controlled
  mechanical , chemical and biological
  properties
  5.4 Developing methods of fabricating composite
  biodegradable hydrogels using IPNs
  5.5 Engineering approaches to deliver growth
  factors from hydrogels
  5.6 Drug delivery systems using polymeric
  hydrogel
  References
  Chapter 6 Surface treatment of biomedical materials
  6.1 Chemical method
  6.2 Electrochemical method
  6.3 Plasma method
  6.4 Ion beam implantation
  6.5 Characterization technique
  Reference
  Chapter 7 3D In Vitro Systems for Biological Application
  7.1 Introduction
  7.2 3D In Vitro Systems
  7.3 3 D Cellular Microenvironment
  7.4 3D Technology on Frontier of Neuroscience
  7.5 Regenerative medicine therapy
  7.6 Future prospects
  References
  Chapter 8 Cell and Gene Therapy based on Biomaterials
  Technology
  8.1 Introduction
  8.2 Engineering Cellular Environment
  8.3 Combinatorial Cell/Polymer Interaction
  Studies
  8.4 Biomaterial Control of Mesenchymal Stem
  Cell Differentiation
  8.5 Biomaterial Control of Embryonic Stem Cell
  Differentiation
  8.6 Classification of cellular barriers systems
  8.7 Calissification of gene delivery systems
  References
  Chapter 9 Nanotechnology inMedicine
  9.1 Introduction
  9.2 Classification of nanomaterials
  9.3 Nanocarriers
  9.4 Nanoscaffoling Materials
  9.5 Biocompatibility and toxicity of nanomaterials
  9.6 Safety issue of nanomaterials
  9.7 Limitations of nanomaterials technology in
  nature and medicine
  9.8 Future Prospects
  References